Brittani Kline

In 2011, Kline appeared in Cycle 16 of the CW Network reality television show, America's Next Top Model, in which she competed against thirteen other aspiring models. She beat out Molly O'Connell in the end, taking the position as Cycle 16 winner.

On the first three episodes, her photos had impressed the judges, finishing her as runner-up for best photo and 3rd on Episode 3. On Episode 4, the judges were disappointed by her performance which was a commercial for Fierce Roast Coffee. Also on episodes 5 and 6, her photos again impressed the judges allowing her to receive runner-up photo on Episode 5 and best photo on Episode 6, as she stood out amongst the brunette group. On Episode 7, one of the most dramatic panels in Top Model history, she was placed on the bottom two together with fellow contestant, Mikaela Schipani caused by her angry confrontation with fellow contestant, Alexandria Everett in which she called her fake in front of the client and in front of panel said that Nigel made the wrong choice in the challenge winner, where the judges' decision were divided with Tyra Banks being the only one who wanted her to leave. As the episode that follows , she apologized to Banks and Banks accepted it. On episodes 10 and 11, her photos again praised the judges and received runner-up on a total of five runner-ups on the whole competition. On Episode 12, she was placed on the bottom two along with fellow contestant, Hannah Jones but was still saved due to the deliberation by the judges.

On the season finale, together with fellow contestant, Molly O'Connell, they shot their CoverGirl commercial and print ad and their Beauty in Vogue spreads. They also met Ivan Bart, the president of IMG Models. On the final runway show, she walked with O'Connell and slipped on the rose petals and crashed into a wall, but the judges praised her when she was still smiling on the finale without showing any pain. As the panel goes on, she and O'Connell received another makeover in which their hair was cut significantly shorter. Her runway was praised but Banks did not like it when she burst into laughter while posing with O'Connell. Her CoverGirl commercial and print ad were also praised. As the judges deliberated, the critique was in Kline's favor. Banks announced her as the winner of the 16th Cycle, placing fellow contestant O'Connell as runner-up. She won a $100,000 contract with CoverGirl Cosmetics, a contract with IMG Models, the cover of Beauty In Vogue and fashion spreads in Vogue Italia and Beauty In Vogue.